Eugene Clark studied printmaking at the Center for Creative Studies, under the direction of James Poole.​ While pursuing his BFA he worked in lithography, etching, aquatint, embossing, collagraph, and monoprint.

His post-graduate study began at Cranbrook Academy of Art, studying printmaking under the direction of Steve Murakishi.

He began working with screen printing.

His post-graduate study continued at Wayne State University where he received his MFA. Here he began his integration of screen printing with drawing.